Bionetic
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Bionetic
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Bionetic
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Vitamins D3 and K2 are two fat-soluble vitamins whose complementary roles in calcium metabolism make co-administration scientifically essential. Vitamin D3 upregulates intestinal calcium absorption via TRPV6 transporter expression and stimulates osteocalcin synthesis in osteoblasts — but osteocalcin must be carboxylated by vitamin K2-dependent gamma-glutamyl carboxylase to achieve its calcium-binding function. Without adequate K2 to activate osteocalcin and matrix Gla protein (MGP), the calcium mobilised by D3 may deposit in arterial walls rather than bone — a paradox resolved by the D3 + K2 combination. The long-chain MK-7 form of K2 provides a 72-hour serum half-life versus the 6–8 hours of MK-4, ensuring continuous carboxylation of bone proteins throughout the day.
Key Capabilities
Supplement Facts
| Per serving | % NRV | |
|---|---|---|
| Vitamin D3 (as Cholecalciferol) | 35 µg | 700% |
| Vitamin K2 (as Menaquinone-7, MK-7) | 100 µg | 133% |
% NRV = % Nutrient Reference Value. A dash (—) indicates no reference value has been established.
Other ingredients: Capsule shell: gelatin; anti-caking agent: magnesium salts of fatty acids; bulking agent: microcrystalline cellulose.
Key Features
Synergistic D3 + K2 MK-7 partnership for calcium direction into bone
K2 MK-7 carboxylates osteocalcin and matrix Gla protein (MGP)
Prevents arterial calcium deposition by activating MGP
Vitamin D3 upregulates intestinal TRPV6 calcium absorption
MK-7 form provides 72-hour half-life for sustained K2 activity
Supports bone density, immune modulation, and arterial wall health
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