Bionetic
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Bionetic
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Bionetic
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Citicoline (cytidine-5-diphosphocholine, CDP-choline) is an endogenous nucleotide that occupies a pivotal position in the Kennedy pathway — the primary route for de novo phosphatidylcholine synthesis in the brain. Upon oral ingestion, citicoline is hydrolysed to choline and cytidine; choline elevates acetylcholine synthesis and drives phosphatidylcholine membrane repair, while cytidine is converted in the brain to uridine, further amplifying phosphatidylcholine production. Unlike plain choline supplements, citicoline simultaneously increases dopaminergic neurotransmission by augmenting dopamine receptor density — an effect documented in neuroimaging studies showing increased striatal dopamine transporter availability after citicoline supplementation. Multiple randomised trials in stroke recovery, traumatic brain injury, glaucoma, and age-related cognitive decline confirm citicoline's neuroprotective and neurorestorative efficacy.
Key Capabilities
Supplement Facts
| Per serving | |
|---|---|
| Citicoline (CDP-choline) | 500 mg |
Other ingredients: Capsule shell: gelatin; anti-caking agent: magnesium salts of fatty acids; bulking agent: microcrystalline cellulose.
Key Features
Pivotal Kennedy pathway intermediate for neuronal phosphatidylcholine synthesis
Elevates brain acetylcholine levels for memory and cholinergic function
Cytidine converts to uridine, amplifying synaptic membrane biosynthesis
Increases dopamine receptor density — neuroimaging-confirmed effect
Clinically validated in stroke recovery, TBI, and cognitive decline
Supports neuronal membrane repair and neuroprotection after injury
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