Green Tea Extract

Green tea extract standardised for epigallocatechin gallate (EGCG) provides the most biologically active polyphenol in Camellia sinensis leaves. EGCG's antioxidant potency derives from its ability to donate hydrogen atoms to neutralise reactive oxygen and nitrogen species, chelate redox-active metals, and activate the Nrf2 antioxidant transcription factor — inducing phase II detoxification enzymes including glutathione S-transferase and NAD(P)H quinone oxidoreductase. EGCG simultaneously inhibits catechol-O-methyltransferase (COMT) — the enzyme that degrades catecholamines — and inhibits fatty acid synthase (FASN), contributing to thermogenic and anti-obesity effects observed in multiple meta-analyses. Cardiovascular benefits are documented across 20+ randomised trials, including reduced LDL oxidation, improved endothelial nitric oxide bioavailability, and decreased platelet aggregation.