Bionetic
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Bionetic
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Bionetic
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Alpha-lipoic acid (ALA) is a naturally occurring dithiol compound unique among antioxidants for its activity in both water-soluble and fat-soluble cellular compartments — allowing it to quench free radicals in the cytoplasm, cell membranes, and mitochondrial matrix simultaneously. ALA is an essential cofactor of the mitochondrial pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. As a potent antioxidant, ALA and its reduced form dihydrolipoic acid (DHLA) regenerate glutathione, vitamins C and E, and coenzyme Q10 from their oxidised forms — functioning as a 'master antioxidant recycler.' Randomised trials in type 2 diabetes confirm ALA at 600 mg/day significantly reduces fasting blood glucose and HbA1c by improving insulin receptor signalling via PI3K-Akt pathway activation, while reducing diabetic peripheral neuropathy symptoms.
Key Capabilities
Supplement Facts
| Per serving | |
|---|---|
| Alpha-lipoic acid (ALA) | 250 mg |
Other ingredients: Capsule shell: gelatin; anti-caking agent: magnesium salts of fatty acids; bulking agent: microcrystalline cellulose.
Key Features
Active in both aqueous and lipid phases — universal cellular antioxidant
Regenerates glutathione, vitamins C, E, and CoQ10 from oxidised forms
Essential cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase
Reduces fasting blood glucose and HbA1c via PI3K-Akt insulin signalling
Clinically shown to reduce diabetic peripheral neuropathy symptoms
DHLA form provides the most potent intracellular antioxidant recycling capacity
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